Nanomedicine: a great hope from the small world

Image courtesy of Brookhaven National Laboratory at Flickr.com

A new interdisciplinary field of medical science is currently in the making. Its methods only leave the laboratories, and most of them still exist only in the form of projects. However, most experts believe that it is these methods that will become fundamental in the 21st century. For example, the National Institutes of Health of the United States have included nanomedicine in the top five priority areas of medical development in the 21st century, and the National Cancer Institute is going to apply the achievements of nanomedicine in the treatment of cancer. A number of foreign scientific centers have already demonstrated prototypes in the fields of diagnostics, treatment, prosthetics, and implantation.

“Nanomedicine is a medical application of nanotechnology. Nanomedicine extends from the medical use of nanomaterials to nanoelectronic biosensors and even the possible use of molecular nanotechnology in the future”.

Nanomedicine aims to provide a significant set of research tools and clinically useful devices in the near future. The National Nanotechnology Initiative is looking forward to new commercial applications in the pharmaceutical industry that may include advanced drug delivery systems, new forms of therapy and imaging in vivo. Neural electronic interfaces and other nanoelectronic sensors are another active goals for research.

Societies are constantly looking for ways to improve health, in terms of costs, coverage, effectiveness, response to emerging diseases, and demographic changes. Nanotechnology has been critically examined to determine how the new capabilities it represents can be applied to current medical needs. Because nanotechnology inherits its approach to certain diseases derived from current medical research, its main objective has been towards non-infectious diseases e.g. cancer, and degenerative diseases.

Some developments in biomedicine at the nanoscopic level have the potential to create new generations of medical implants that are designed to interact with the body, monitor the chemical composition of blood and, if necessary, release certain medications. Bones, cartilages, and artificial skins that in addition to not being rejected by the body, seek to help some parts of the human body to regenerate. There are also new systems for diagnosis, imaging, and regeneration; in this way, it is intended that the side effects of current systems and/or procedures be mitigated.

A classic in the field of nanotechnology developments and predictions, Eric Drexler in his fundamental works described the main methods of treatment and diagnosis based on nanotechnology. The key problem to achieve these results is the creation of special medical nanorobots - nanomachines for repairing cells. Medical nanorobots should be able to diagnose diseases, circulating in the human blood and lymphatic systems and moving in the internal organs, deliver drugs to the affected area and even do surgical operations. Drexler also suggested that medical nanorobots would provide an opportunity to revitalize people frozen by cryonics.

Achievements of nanomedicine will become widely available by different estimates only after 40-50 years. However, a number of recent discoveries, developments, and investments in the nanotechnology have led to the fact that more and more analysts are shifting this date for 10-15 years downwards.

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So far, nanomedicine is a large industry, where sales reached 6.8 billion dollars more than a decade ago. In this industry, there are more than two hundred active companies, in which at least $ 3.8 billion are invested annually.

Two types of nanomedicine have just been tried in mice and are now required to be tried in people. We are talking about the application of gold nanocapsules for analyzing and guiding the antibodies as a vehicle for medical solutions. Those gold nanoparticles are composed of clusters of gold atoms prepared from the reduction of gold salts. Due to changes in their surface plasmon resonance, gold nanoparticles can be used for colorimetric assays. By means of the control of the aggregation of gold nanoparticles, it has been possible to detect matrices of biomolecules.

Image courtesy of BASF - We create chemistry at Flickr.com

Similarly, disposing of the lethality of medications is another use of nanomedicine, which has indicated promising outcomes in rats. The advantage of introducing nanoscale gadgets in therapeutic innovations is that those little gadgets are not so obtrusive, and they can be embedded inside the organism, and, what's more, their biochemical responses are much quicker. These gadgets work faster and end up being more practical, even more than the traditional ways.

The nanobots of nanomedicine could be produced with the function of restructuring or repairing muscles or bony tissues. Fractures could be a thing of the past, nanobots could be programmed to identify fissures in bones and fix these in two ways; performing some process to accelerate the recovery of the broken bone or melting with the broken bone or even both, and thus with an infinity of diseases of various types dissolving substances of multiple varieties according to, in blood or in the area to be treated specifically, injecting small amounts of antibiotics or antiseptics in case of colds or inflammations, etc.

Currently, silver nanoparticles are being used as disinfectants and antiseptics in pharmaceutical and surgical products, in underwear, gloves, socks and sports shoes, in baby products, personal hygiene products, cutlery, refrigerators, clothes washers and all type of implantable materials.

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